Description
REXO2 is a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to uV-C-induced cell death through its role in the DNA repair process. Recombinant human REXO2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques